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Is growing older an engineering drawback or a call?

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At the India Today Conclave 2025, the dialog grew to become to what may well be without equal human aspiration, now not simply delaying loss of life however wondering if growing older itself can also be re-engineered. Dr Avi Roy, biomedical scientist, entrepreneur, and co-founder of Founders Health and the London Longevity Club, led the dialogue with provocative readability.

“Immortality, I don’t assume any actual related scientist is pondering of,” Dr Roy clarified on the outset. “But we’re pondering of negligible senescence or recall to mind it as practical immortality.”

He defined that immortality within the vampire or science-fiction sense used to be a distraction. Instead, longevity science research animals just like the bowhead whale, which will reside for as much as 300 years, resisting age-related illnesses like most cancers. “What you’re is extra like a bowhead whale as a substitute of a box mouse. A box mouse hardly ever lives past six months, whilst a bowhead whale can reside 3 centuries.”

ENGINEERING AGEING: THE SCIENCE OF LONGEVITY

For Dr Roy, growing older isn’t future, it’s an engineering problem. “For 99% of our lifestyles, 40% of youngsters died earlier than their 5th birthday. We solved that now not through magic, however with engineering, vaccines had been necessarily device upgrades for the immune gadget.”

Now, the point of interest is on adults. Scientists have known 13 hallmarks of growing older from telomere attrition to mobile rubbish accumulation and verbal exchange breakdowns. “If we will be able to goal and opposite them, you want to both come again on your 30s or keep on your 30s for centuries,” Roy stated.

While those breakthroughs are nonetheless examined handiest in worms, mice, and early dog research, the roadmap is obvious: growing older is also slowed, paused, and even reversed.

THE INDIAN PARADOX: SADHUS AT 90, HEART ATTACKS AT 30

India, with its contradictions, supplies a singular lens on longevity. “This is a rustic the place Sadhus and Rishis have lived 90-plus years with out fashionable medication and the similar nation the place 30-year-olds die of surprising cardiac arrest. That complexity is why India has such a lot to give a contribution to the science of growing older,” he stated.

Conclave Mumbai Full Coverage

PERSONALISED MEDICINE AND INDIA’S DATA EDGE

One of the most important shifts in healthcare is personalisation. “In the United Kingdom’s NHS, we’ve got 70 million birth-to-death data. That shall we us examine remedies throughout populations to look which really prolong now not simply lifestyles, however wholesome lifestyles. India can leapfrog with its virtual well being challenge, the Aadhaar card may create the sector’s biggest healthcare dataset, enabling in-silico scientific trials at scale,” Roy defined.

This opens the door to AI-driven drug personalisation, making sure remedies align with particular person genetics, way of life, and possibility components.

TELOMERES, GENE THERAPY, AND THE HYPE VS. REALITY

Much of public fascination with longevity comes from buzzwords like telomeres and gene treatment. Roy drew a boundary: “Telomeres are like shoelace caps, they fray when cells divide. But that’s handiest certainly one of 13 hallmarks of growing older. We don’t but have confirmed fixes for telomeres in people, despite the fact that trials are underway for illnesses like dementia.”

The hype, he argued, regularly runs forward of pragmatic breakthroughs. But the course is promising.

THE LONGEVITY ROUTINE: WHAT DR ROY DOES HIMSELF

When requested about his personal longevity regimen, Dr Roy didn’t hesitate: “You will have to all the time take your personal medication. I take GLP-1s. Not for weight reduction, however for longevity.”

GLP-1 receptor agonists, at the start designed for diabetes, at the moment are repurposed for weight reduction globally. But early research display they might also cut back irritation, keep an eye on urge for food, and strengthen metabolic well being. “After two weeks, there used to be no meals noise. You can in truth do different issues along with your lifestyles. That in itself is releasing,” he stated.

Beyond drugs, his recommendation is unassuming however evidence-backed:

  • Maintain robust VO max (cardio capability)
  • Build muscles and grip energy
  • Track and arrange biomarkers with the similar seriousness as budget

“Look at your well being portfolio like your monetary one. If you don’t need a middle assault at 55 like your father, you want to observe the markers causally related to it and stay them in vary.”

THE MENTAL COST OF GADGET TRACKING

Of route, this obsession with longevity comes at a price. Dr Roy wore 3 monitoring units on level, prompting a query: does measuring each and every breath and chew erode psychological peace?

“Absolutely. It’s an obsession on the finish of the day. But that is the bumpy street. Wearables and medication are simply stepping stones. One day, like cervical most cancers disappearing thru HPV vaccines, we’ll engineer growing older so totally that you simply received’t want trackers in any respect.”

AYURVEDA MEETS SCIENCE

As an India-specific query, Dr Roy used to be requested whether or not conventional knowledge like Ayurveda can converge with fashionable science. His resolution used to be unequivocal:

“India has all the time been a melting pot. From Ayurveda to AI, from wheat fields to the Silk Road, we’ve got absorbed and scaled concepts. I consider India can amalgamate, incorporate, and scale the way forward for longevity like no different position on the earth.”

THE BASICS FOR SOUTH ASIA

When pressed for fast hacks, Roy refused to oversell. “Honestly, it boils all the way down to what Ayurveda has been pronouncing all alongside devour neatly, sleep neatly, cut back rigidity. Aerobic workout, muscle energy, and grip energy are probably the most scientifically validated hacks for South Asians.”

But his actual “hack” used to be sharper, monitoring. “Even one-time dimension of blood markers in comparison to circle of relatives historical past can expose dangers. Once you spot the ones purple flags, you’ll’t unsee them. Then you act.”

FINAL WORD: DEATH, A CHOICE?

In the tip, Dr Roy framed longevity now not as myth, however as company. “We don’t seem to be breaking physics. We are merely asking, do we need to age this rapid? Today, you might have empowerment. You don’t wish to blindly practice authority. You have information, medical doctors, and AI. The selection is yours.”

As he closed, the target audience used to be left with a concept each exciting and unsettling: We all die. But what if, in the future, we didn’t need to?

– Ends

Published By:

vaishnavi parashar

Published On:

Sep 25, 2025

Source: www.indiatoday.in

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